Biography
Ali Namvaran (D.V.M, Ph.D.)
University of Nebraska Medical Center (UNMC)
United States
Dr. Ali Namvaran, DVM, Ph.D., is a Postdoctoral Research Associate in the Department of Pharmacology and Experimental Neuroscience at the University of Nebraska Medical Center (UNMC), USA. His current work focuses on HIV-associated cardiovascular complications, including mitochondrial dysfunction, oxidative stress, and sudden cardiac death mechanisms in humanized mouse models. He has also served as an Assistant Professor at the Azad University and as Medical and Marketing Manager at Zahravi Pharmaceutical Co., collaborating with Roche Hoffmann in drug development and production projects. Dr. Namvaran’s research background spans neuroscience, cancer pharmacology, pain modulation, and neurodegenerative disorders, with emphasis on plant-derived bioactives and pharmacological screening. He has published widely, presented at international conferences, and serves on the editorial boards of several biomedical journals. His expertise integrates molecular pharmacology, animal modeling, and translational research.
Research Interests
- Neuroscience and cancer pharmacology, particularly innovative strategies for treating colorectal cancer using rodent models, cell lines, and plant-based bioactives.
- Pain modulation and chemotherapy-induced neuropathy, with a focus on the antinociceptive effects of herbal agents against drugs like Cisplatin, Vincristine, and Methotrexate.
- Neurodegenerative disorders, including histopathological studies of Alzheimer’s disease and experimental models of seizures.
- Diabetes and metabolic disease models, including induction of neuropathic pain and evaluation of hepatotoxicity.
- Advanced pharmacognosy and drug delivery, with expertise in extraction of plant compounds, antibiotic resistance testing, and in vivo/in vitro pharmacological screening.
- Cardiovascular complications in HIV-infected individuals, particularly:
- Mechanisms of sudden cardiac death, mitochondrial dysfunction, and oxidative stress under antiretroviral therapy.
- Assessment of methylglyoxal as a novel cardiotoxic biomarker in HIV models.
- Non-invasive measurement tools for estimating blood pressure using ECG and Doppler ultrasound in humanized mouse models.
- Cardiac fibrosis, arrhythmias, and multi-organ involvement in chronic HIV infection.